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Genetics and Genomics

 

Phenotype of golden zebrafish. Lateral views of adult wild-type (A) and golden (B) zebrafish. Insets show melanophores (arrow- heads). Scale bars, 5 mm (inset, 0.5 mm). golb1 mutants have melanophores that are, on av- erage, smaller, more pale, and transparent. Transmission electron micrographs of skin mel- anophore from 55-hpf wild-type (C and E) and golb1 (D and F) larvae. golb1 skin melanophores (arrowheads show edges) are thinner and con- tain fewer melanosomes than do those of wild type. Melanosomes of golb1 larvae are fewer in number, smaller, less-pigmented, and irregular compared with wild type. Scale bars in (C) and (D), 1000 nm; in (E) and (F), 200 nm.  (Cheng KC. SLC24A5, a putative cation exchanger, affects pigmentation in zebrafish and humans. Science. 2005 Dec 16; 310(5755):1782-6.)

Images provided by Cheng Lab.

Labs Performing This Type of Research

Broach Lab

Carrel Lab

Cheng Lab

Eckert Lab

Gerhard Lab

Grigoryev Lab

Ishmael Lab

Keil Lab

Moldovan Lab

Notterman Lab