Biochemistry & Molecular Biology

Jacob Hornick, Broach Lab Member, Passes His Comprehensive Exam

krh223 — Fri, 10 May 2013 18:30:33 +0000

Friday, April 26, 2013 Jacob Hornick, 3rd Year Biochemistry Student, passed his comprehensive examination written on the effects of oxytocin receptor localization to the progression of prostate cancer. As a full time member of the Broach lab, Jacob will be studying human G protein-coupled receptor signaling using yeast as a biological platform.

New Study Out of Moldovan Lab

krh223 — Fri, 10 May 2013 17:44:10 +0000

Thursday, May 9, 2013 A new study from the Moldovan laboratory offers preclinical proof-of-concept for a novel candidate therapeutic target to treat this deadly disease. The study, published in April 15 in the journal “Cancer Research” shows that an element of the homologous recombination pathway of DNA repair, the PARP-binding protein C12orf48/PARI (PARPBP), is overexpressed …

Moldovan Lab Adds New BMS Student

krh223 — Fri, 10 May 2013 17:43:10 +0000

Thursday, May 9, 2013 Katherine Choe, 2nd year graduate student in the Biomedical Science Graduate Program, joined the Moldovan Lab. Kat graduated from University of Sciences in Philadelphia in 2011 with her B.S. in Pharmacology andm Toxicology. Previously, she worked as a Laboratory Assistant at the Wistar Institute in Philadelphia. She will be investigating the mechanisms …

Dr. Keil Honored with AAMC Award

krh223 — Fri, 12 Oct 2012 13:23:07 +0000

Dr. Ralph Keil, Associate Professor in Biochemistry and Molecular Biology at Penn State College of Medicine, has been named as a recipient of the inaugural Association of American Medical Colleges (AAMC) Award for Innovations in Research Training and Education. Dr. Keil’s winning abstract was titled Interdisciplinary Graduate Education in Biomedical Sciences. The major goal of the …

Biochemistry & Molecular Biology Department Retreat 2012

krh223 — Thu, 13 Sep 2012 12:37:29 +0000

First Annual Biochemistry and Molecular Biology Departmental Retreat Saturday, October 6, 2012 8:30 AM - 5 PM University Conference Center Photos from the 2012 Retreat and BBQ

Penn State Hershey launches Institute for Personalized Medicine

krh223 — Fri, 24 Feb 2012 17:44:36 +0000

Friday, February 24, 2012 Penn State Milton S. Hershey Medical Center and Penn State College of Medicine have launched the Penn State Hershey Institute for Personalized Medicine, which will bring together faculty, resources and programs devoted to advancing the relatively new field of personalized medicine, one of the most promising frontiers in medicine. The new institute will work …

Penn State Hershey Health System Showcases Awards and Honors

krh223 — Thu, 20 Oct 2011 17:45:48 +0000

Thursday, October 20, 2011 To recognize the achievements of faculty, staff, students, and volunteers at Penn State Milton S. Hershey Medical Center and Penn State College of Medicine, the following list of appointments, awards and honors that may be of public interest has been compiled for the quarter of July 1 to September 30, 2011. …

Cancer Biology

krh223 — Tue, 31 May 2011 18:53:54 +0000

A. 2D-DIGE and immunoblot analysis were employed in a well-defined lung carcinogenesis mouse model to identify potential protein biomarkers of lung cancer. Down-regulation of 14-3-3 isoforms and annexin A5, observed in lung adenocarcinomas from mice treated with the tobacco-specific carcinogen NNK, were subsequently recovered in the lungs of mice treated with the chemopreventive agent p-XSC. …

Structural Biology

krh223 — Tue, 31 May 2011 18:53:42 +0000

Changes in the structure of the dimeric C-terminal domain of the Raus sarcoma virus with mutation. D155Y-CTD is a lethal mutation that is not infective and does not dimerize. R185W-CTD has a 20-fold tighter dimerization affinity and is nearly as infective as WT-CTD. The double mutant D155Y/R185W-CTD has a dimerization affinity that is 10 fold …

Genetics and Genomics

krh223 — Tue, 31 May 2011 16:42:55 +0000

Phenotype of golden zebrafish. Lateral views of adult wild-type (A) and golden (B) zebrafish. Insets show melanophores (arrow- heads). Scale bars, 5 mm (inset, 0.5 mm). golb1 mutants have melanophores that are, on av- erage, smaller, more pale, and transparent. Transmission electron micrographs of skin mel- anophore from 55-hpf wild-type (C and E) and …