A good place to start your research is the NIH website, which provides an overview of all career development grant mechanisms and the currently active Funding Opportunity Announcements (FOAs). Keep in mind that FOAs can be issued through either a Parent Announcement or an IC-specific FOA. What is the difference? NIH Parent Announcements are agency-wide FOAs that enable applicants to submit investigator-initiated applications to multiple ICs. ICs that participate in an NIH Parent Announcement may have supplemental requirements, so it is important to speak with the program officer at the IC whose research objectives most closely align with your research before submitting an application. Some ICs may choose not to participate in the NIH Parent Announcement in favor of issuing a targeted FOA that focuses on increasing research strength in a specific field of biomedical research or attracting researchers from underrepresented backgrounds.